Dear Friends,

I am excited to share that I have begun my annual Pedal4Paul bike-ride training!!  I am looking forward to another successful event on June 22, and hope that with every street I pass, with every milestone I reach on my 14.3 mile ride, it brings the ML4 Foundation closer to reaching its goal of finding the treatments for ML4.  With your continued generosity, I know we can do this!  Please donate today by clicking the donate button on this page. All donations will go directly to the ML4 Foundation, and Paul, Allan, and I thank you for your concern, consideration, and support of this important event.

Over the past years the ML4 Foundation has sponsored research in gene therapy that is now enticingly close to a treatment stage. Researchers have shown in animal models that this treatment can significantly repair this disease, and the doctors and scientists have met with the FDA to plan a clinical trial of this therapy. These extraordinary steps forward only happen with support like yours!

I started this ride 10 years ago, first through the streets of Philadelphia, continued throughout the “Covid years” in New York, and I will continue as long as it takes!! Our goals are within reach, and it is all due to your commitment to helping us support our researchers. Again, click today to make your donation and thank you all!!


ML4 is a genetic disease caused by the mutation of a single gene that results in the loss of a protein (MCLN1). This incredibly important protein is required by the body for normal functioning: without MCLN1, children and adults with ML4 suffer from progressive and debilitating loss of gross and small motor function, go blind, develop problems chewing and swallowing, rarely have the ability to speak, cannot walk, and over time, lose many abilities that they work hard to acquire when they are young.

The funds raised by the ML4 Foundation are directed to a research program at Massachusetts General Hospital in Boston. We have been working for several years with a team there to create a gene therapy to treat ML4. We are also funding a large-scale natural history study of ML4, bringing ML4 patients from around the world to the MGH clinic to be seen by specialists in this disease. YOUR DONATIONS made this work possible and allow it to continue at a speedy pace!

If you prefer to donate by check, you may mail it to the following address, and note that it is given in honor of Paul Kutner.

Mucolipidosis IV Foundation
1440 Spring Street NW
Atlanta, Georgia 30309

The ML4 Foundation is a U.S. 501 (c)(3) nonprofit charitable organization.
Tax ID 13-3633501